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They found patients prescribed semaglutide (a glucagon-like peptide receptor, or GLP-1R) had a significantly lower risk for Alzheimers disease, compared to those who had taken any of seven other anti-diabetic medications, including other types of GLP-1R-targeting medications
Adiposity, hyperinsulinemia, diabetes and Alzheimers disease: an epidemiological perspective
The first step involves the binding of the extracellular domain to the C-terminus of the ligand
Biophys Chem 267:106474
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